| Week | Date | Time | Opponent | Outcome | |
|---|---|---|---|---|---|
| Pre | 8/10/12 | 7:30pm EDT | New York Jets | Win 17-6 | Box Score |
| Pre | 8/16/12 | 8:00pm EDT | at Atlanta Falcons | Win 24-19 | Box Score |
| Pre | 8/23/12 | 7:00pm EDT | Green Bay Packers | Loss 13-27 | Box Score |
| Pre | 8/30/12 | 7:00pm EDT | at Indianapolis Colts | Loss 16-20 | Box Score |
| 1 | 9/10/12 | 7:00pm EDT | at Baltimore Ravens | Loss 13-44 | Box Score |
| 2 | 9/16/12 | 1:00pm EDT | Cleveland Browns | Win 34-27 | Box Score |
| 3 | 9/23/12 | 1:00pm EDT | at Washington Redskins | Win 38-31 | Box Score |
| 4 | 9/30/12 | 4:05pm EDT | at Jacksonville Jaguars | Win 27-10 | Box Score |
| 5 | 10/07/12 | 1:00pm EDT | Miami Dolphins | Loss 13-17 | Box Score |
| 6 | 10/14/12 | 1:00pm EDT | at Cleveland Browns | Loss 24-34 | Box Score |
| 7 | 10/21/12 | 8:20pm EDT | Pittsburgh Steelers | Loss 17-24 | Box Score |
| 8 | BYE WEEK | OFF DATE | NONE | ||
| 9 | 11/04/12 | 1:00pm EDT | Denver Broncos | Loss 23-31 | Box Score |
| 10 | 11/11/12 | 1:00pm EDT | New York Giants | Win 31-13 | Box Score |
| 11 | 11/18/12 | 1:00pm EDT | at Kansas City Chiefs | Win 28-6 | Box Score |
| 12 | 11/25/12 | 1:00pm EDT | Oakland Raiders | Win 34-10 | Box Score |
| 13 | 12/2/12 | 4:25pm EDT | at San Diego Chargers | Win 20-13 | Box Score |
| 14 | 12/9/12 | 1:00pm EDT | Dallas Cowboys | Loss 19-20 | Box Score |
| 15 | 12/13/12 | 8:20pm EDT | at Philadelphia Eagles | Win 34-13 | Box Score |
| 16 | 12/23/12 | 1:00pm EDT | at Pittsburgh Steelers | Win 13-10 | Box Score |
| 17 | 12/30/12 | 1:00pm EDT | Baltimore Ravens | Win 23-17 | Box Score |
| Wild Card | 1/5/13 | 4:20pm EDT | at Houston Texans | Loss 13-19 | Box Score |